• Protein Degradation by E3 Ubiquitin Ligases in Cancer Stem Cells [Review] 

      Quiroga Fernández, Macarena; Rodríguez-Alonso, Andrea; Alfonsín Rey, María Gloria; Escuder-Rodríguez, Juan-José; Breijo, Sara M.; Chantada, Venancio; Figueroa, Angélica (MDPI, 2022-02-16)
      [Abstract] Cancer stem cells are a small subpopulation within the tumor with high capacity for self-renewal, differentiation and reconstitution of tumor heterogeneity. Cancer stem cells are major contributors of tumor ...
    • Role of the E3 Ubiquitin-Ligase Hakai in Intestinal Inflammation and Cancer Bowel Disease 

      Roca-Lema, Daniel; Quiroga, Macarena; Khare, Vineeta; Díaz-Díaz, Andrea; Barreiro-Alonso, Aida; Rodríguez-Alonso, Andrea; Concha, Ángel; Romay, Gabriela; Cerdán, María Esperanza; Gasche, Christoph; Figueroa, Angélica (Springer Nature, 2022-10-20)
      [Abstract] The E3 ubiquitin-ligases are important for cellular protein homeostasis and their deregulation is implicated in cancer. The E3 ubiquitin-ligase Hakai is involved in tumour progression and metastasis, through the ...